A Mathematical model for carbon dioxide exchange during mechanical ventilation with Tracheal Gas Insufflation (TGI)

Effect of tracheal gas insufflation during weaning from prolonged mechanical ventilation: a preliminary study.

BACKGROUND Tracheal gas insufflation reduces inspired tidal volume and minute ventilation in spontaneously breathing patients and may facilitate weaning from mechanical ventilation. OBJECTIVE To determine if tracheal gas insufflation can reduce ventilatory demand during weaning trials in patients who require prolonged mechanical ventilation. METHODS A reduction in ventilatory demand was def...

Ventilation-perfusion distributions and gas exchange during carbon dioxide-pneumoperitoneum in a porcine model.

BACKGROUND Carbon dioxide (CO₂)-pneumoperitoneum (PP) of 12 mm Hg increases arterial oxygenation, but it also promotes collapse of dependent lung regions. This seeming paradox prompted the present animal study on the effects of PP on ventilation-perfusion distribution (V/Q) and gas exchange. METHODS Fourteen anaesthetized pigs were studied. In seven pigs, single photon emission computed tomog...

Tracheal gas insufflation: a useful adjunct to ventilation?

Monitoring and humidification during tracheal gas insufflation.

In order to use tracheal gas insufflation (TGI) in a safe and effective manner, it is important to understand potential interactions between TGI and the mechanical ventilator that may impact upon gas delivery and carbon dioxide (CO2) elimination. Furthermore, potentially serious complications secondary to insufflation of cool, dry gas directly into the airway and the possibility of tube occlusi...

Combination of tracheal gas insufflation and airway pressure release ventilation.

STUDY OBJECTIVE We hypothesized that the continuous gas flow administration delivered through an insufflation catheter positioned above the carina during airway pressure release ventilation (APRV) would facilitate carbon dioxide (CO2) elimination, resulting in normocarbia with a substantially reduced peak airway pressure (Paw). To test this hypothesis, we compared intermittent positive pressure...